Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations

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Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations

Across species and tissues and especially in the mammalian brain, production of gene isoforms is widespread. While gene expression coordination has been previously described as a scale-free coexpression network, the properties of transcriptome-wide isoform production coordination have been less studied. Here we evaluate the system-level properties of cosplicing in mouse, macaque, and human brai...

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ژورنال

عنوان ژورنال: Frontiers in Genetics

سال: 2015

ISSN: 1664-8021

DOI: 10.3389/fgene.2015.00174